Brendan Fraser

DJ Drake / Tasmanian Devil (voice) / She-Devil (voice) / Self

Jenna Elfman

Kate

Steve Martin

Mr. Chairman

Joe Alaskey

Bugs Bunny-Daffy Duck / Beaky Buzzard / Sylvester / Mama Bear (voice)

Jeff Bennett

Yosemite Sam / Foghorn Leghorn / Nasty Canasta (voice)

Timothy Dalton

Damien Drake

Billy West

Elmer Fudd / Peter Lorre (voice)

Heather Locklear

Dusty Tails

Joan Cusack

Mother

Bill Goldberg

Mr. Smith

Don Stanton

Mr. Warner

Dan Stanton

Mr. Warner's Brother

Dick Miller

Security Guard

Roger Corman

Hollywood Director

Kevin McCarthy

Dr. Bennell

Jeff Gordon

Self

Matthew Lillard

Self

Mary Woronov

Acme VP, Bad Ideas

Marc Lawrence

Acme VP, Stating the Obvious

Bill McKinney

Acme VP, Nitpicking

George Murdock

Acme VP, Unfairly Promoted

Robert Picardo

Acme VP, Rhetorical Questions

Ron Perlman

Acme VP, Never Learning

Vernon Wells

Acme VP, Child Labor

Leo Rossi

Acme VP, Climbing to the Top

Archie Hahn

Stunt Director

Allan Graf

Interrogator

Austyn Cuccia

Tour Bus Girl

Marie-Claude Jacques

Flower Vendor

Michael Azria

Paris Cafe Waiter

Dan Romanelli

Studio Executive

Kevin Thompson

Dancing Yosemite Sam

Arturo Gil

Dancing Yosemite Sam

Gabriel Pimentel

Dancing Yosemite Sam

Steve Babiar

Dancing Yosemite Sam

Martin Klebba

Dancing Yosemite Sam

Eric Goldberg

Tweety Bird / Marvin the Martian / Speedy Gonzalez (voice)

Bruce Lanoil

Pepe le Pew (voice)

June Foray

Granny (voice)

Bob Bergen

Porky Pig (voice)

Casey Kasem

Shaggy (voice)

Frank Welker

Scooby-Doo (voice)

Danny Chambers

Cottontail Smith (voice)

Stan Freberg

Baby Bear (voice)

Will Ryan

Papa Bear (voice)

Danny Mann

Robo Dog - Spy Car (voice)

Mel Blanc

Gremlin Car (archive sound)

Tara Wilson

Dancer

Tanee McCall

Dancer

Gelsey Weiss

Dancer

Brenda Mae Hamilton

Dancer

Liz Ramos

Dancer

Emily Rose Zachary

Dancer

Becca Sweitzer

Dancer

Janina Garraway

Dancer

Alysha Wheeler

Dancer

Micki Duran

Dancer

Chi Johnson

Dancer

Shealan Spencer

Dancer

Shanti Lowry

Dancer

Brandon Henschel

Dancer

Erica Gudis

Dancer

John Munro Cameron

The Man from Planet X

Peter Graves

Host of Civil Defense Film

Glen Hambly

Laboratory Scientist

Michael Jordan

Self (archive footage)

Louis Kiss

Dalek

Nikki Martin

Wooden Nickel Waitress

Laura Orrico

Secret Agent Shopper

Robert Parigi

Robby the Robot

Dean Ricca

Studio Tour Guide

Tom Woodruff Jr.

The Metaluna Mutant (uncredited)